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中文名称：兔抗ACOT8多克隆抗体
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Background: |
The protein encoded by this gene is a peroxisomal thioesterase that appears to be involved more in the oxidation of fatty acids rather than in their formation. The encoded protein can bind to the human immunodeficiency virus-1 protein Nef, and mediate Nef-induced down-regulation of CD4 in T-cells. Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. May mediate Nef-induced down-regulation of CD4. Major thioesterase in peroxisomes. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ACOT8 |
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Immunogen: |
Fusion protein of human ACOT8 |
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Full name: |
acyl-CoA thioesterase 8 |
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Synonyms： |
hTE; PTE1; PTE2; PTE-1; PTE-2; HNAACTE; hACTE-III |
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SwissProt: |
O14734 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human cervical cancer and human thyroid cancer |
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IHC Recommend dilution: |
15-50 |
