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021-54888888/15800441009
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Background: |
Adapter protein which acts downstream of several membrane receptors including cytokine, antigen, hormone, cell matrix and growth factor receptors to regulate multiple signaling pathways. Regulates osteoclast differentiation mediating the TNFRSF11A/RANK signaling. In allergic response, it plays a role in mast cells activation and degranulation through PI-3-kinase regulation. Also involved in the regulation of cell proliferation and hematopoiesis. |
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Applications: |
WB, IHC |
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Name of antibody: |
GAB2(Ab-159) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human GRB2 around the phosphorylation site of serine 159 (K-S-S(p)-A-P). |
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Full name: |
GRB2-associated binding protein 2 |
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Synonyms： |
KIAA0571 |
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SwissProt: |
Q9UQC2 |
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IHC positive control: |
Human colon carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
74 kDa |
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WB Positive control: |
COS cells lysate |
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WB Recommended dilution: |
500-3000 |
