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021-54845833/15800441009
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Background: |
This gene encodes a voltage-activated potassium channel belonging to the eag family. It shares sequence similarity with the Drosophila ether-a-go-go (eag) gene. Mutations in this gene can cause long QT syndrome type 2 (LQT2). Transcript variants encoding distinct isoforms have been identified. Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoform 3 has no channel activity by itself, but modulates channel characteristics when associated with isoform 1. |
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Applications: |
ELISA, WB |
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Name of antibody: |
KCNH2 |
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Immunogen: |
Synthetic peptide of human KCNH2 |
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Full name: |
potassium voltage-gated channel, subfamily H (eag-related), member 2 |
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Synonyms： |
ERG1, HERG, LQT2, SQT1, HERG1, Kv11.1 |
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SwissProt: |
Q12809 |
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ELISA Recommended dilution: |
1000-5000 |
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WB Predicted band size: |
90 kDa |
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WB Positive control: |
Mouse brain tissue |
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WB Recommended dilution: |
500-2000 |
