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Background: |
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Demethylates both di- and trimethylated H3 'Lys-9' residue, while it has no activity on monomethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. |
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Applications: |
ELISA, WB |
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Name of antibody: |
KDM4D |
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Immunogen: |
Synthetic peptide of human KDM4D |
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Full name: |
lysine demethylase 4D |
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Synonyms: |
JMJD2D |
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SwissProt: |
Q6B0I6 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
Human fetal brain tissue lysate |
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WB Recommended dilution: |
500-2000 |
