Fusion protein corresponding to a region derived from 246-445 amino acids of human GDI2 |
技术规格
Full name: |
GDP dissociation inhibitor 2 |
Synonyms: |
RABGDIB; HEL-S-46e |
Swissprot: |
P50395 |
Gene Accession: |
BC005145 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms. |