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Background: |
Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer’s disease. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
LRRC15 |
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Immunogen: |
Fusion protein of human LRRC15 |
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Full name: |
leucine rich repeat containing 15 |
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Synonyms： |
LIB |
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SwissProt: |
Q8TF66 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human prostate cancer and Human cervical cancer |
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IHC Recommend dilution: |
100-300 |
