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Background: |
This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
LRRK2 |
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Immunogen: |
Fusion protein of human LRRK2 |
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Full name: |
leucine-rich repeat kinase 2 |
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Synonyms： |
PARK8; RIPK7; ROCO2; AURA17; DARDARIN |
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SwissProt: |
Q5S007 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
