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Background: |
The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. |
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Applications: |
WB |
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Name of antibody: |
SERPINB8 |
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Immunogen: |
Fusion protein of human SERPINB8 |
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Full name: |
serpin family B member 8 |
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Synonyms: |
PI8; CAP2; HMSD; PI-8; PSS5; HSMD-v; C18orf53 |
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SwissProt: |
P50452 |
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WB Predicted band size: |
43 KD |
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WB Positive control: |
Jurkat, MCF7 cell lysates |
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WB Recommended dilution: |
500-2000 |
