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抗 原： SIRPB1
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Background: |
The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
WB |
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Name of antibody: |
SIRPB1 |
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Immunogen: |
Fusion protein of human SIRPB1 |
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Full name: |
signal regulatory protein beta 1 |
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Synonyms: |
CD172b; SIRP-BETA-1 |
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SwissProt: |
O00241 |
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WB Predicted band size: |
43 KD |
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WB Positive control: |
A549, COS7, MDCK cell lysates |
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WB Recommended dilution: |
200-1000 |
