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021-54845833/15800441009
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Background: |
Peroxiredoxin-5 (PRDX5) is a novel mammalian peroxiredoxin, belonging to the family of thiol-dependent peroxidases. It is structurally dissimilar from other peroxiredoxins in that it contains a conserved cysteine 47 residue at the N-terminus and a cysteine 151 residue at the C-terminus which form an intramolecular disulphide bridge and confers unique chemical characteristics to this enzyme. Peroxiredoxins protect cells from apoptosis induced by overexposure to endogenous or exogenous peroxides, such as peroxynitrites, hydrogen peroxide, and alkyl hydroperoxides. Peroxiredoxin-5 is widely expressed in various subcellular regions, including mitochondria, peroxisomes, nucleus, and cytosol. |
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Applications: |
WB, IHC |
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Name of antibody: |
PRDX5 |
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Immunogen: |
Fusion protein of human PRDX5 |
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Full name: |
peroxiredoxin 5 |
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Synonyms: |
PLP; ACR1; B166; PRXV; PMP20; PRDX6; prx-V; SBBI10; AOEB166; HEL-S-55 |
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SwissProt: |
P30044 |
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IHC positive control: |
Human appendix tissue and Human gastric tissue |
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IHC Recommend dilution: |
100-250 |
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WB Predicted band size: |
22 KD |
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WB Positive control: |
Hela, HepG2, MCF7 cell lysates |
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WB Recommended dilution: |
500-2000 |
