Background: |
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is expressed in germinal center B-cells, placenta and stomach as well as in colon tumor. This gene is down-regulated in intestinal type gastric cancer. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
CLDN23 |
Immunogen: |
Fusion protein of human CLDN23 |
Full name: |
claudin 23 |
Synonyms: |
CLDNL; hCG1646163 |
SwissProt: |
Q96B33 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human brain |
IHC Recommend dilution: |
25-100 |
WB Predicted band size: |
32 kDa |
WB Positive control: |
Hela cells |
WB Recommended dilution: |
200-1000 |