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中文名称：ALG12 抗原（重组蛋白）
英文名称： ALG12 Antigen (Recombinant Protein)
别 名： ALG12, alpha-1,6-mannosyltransferase; CDG1G; ECM39; hALG12; PP14673
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 367-488 amino acids of human ALG12 |
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Full name: |
ALG12, alpha-1,6-mannosyltransferase |
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Synonyms: |
CDG1G; ECM39; hALG12; PP14673 |
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Swissprot: |
Q9BV10 |
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Gene Accession: |
BC001729 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the glycosyltransferase 22 family. The encoded protein catalyzes the addition of the eighth mannose residue in an alpha-1,6 linkage onto the dolichol-PP-oligosaccharide precursor (dolichol-PP-Man(7)GlcNAc(2)) required for protein glycosylation. Mutations in this gene have been associated with congenital disorder of glycosylation type Ig (CDG-Ig)characterized by abnormal N-glycosylation. |
