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中文名称： DACH2抗原（重组蛋白）
英文名称： DACH2 Antigen (Recombinant Protein)
相关类别： 抗原
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Fusion protein corresponding to a region derived from C terminal 230 amino acids of human DACH2 |
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Full name: |
dachshund family transcription factor 2 |
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Swissprot: |
Q96NX9 |
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Gene Accession: |
BC114950 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene is one of two genes which encode a protein similar to the Drosophila protein dachshund, a transcription factor involved in cell fate determination in the eye, limb and genital disc of the fly. The encoded protein contains two characteristic dachshund domains: an N-terminal domain responsible for DNA binding and a C-terminal domain responsible for protein-protein interactions. This gene is located on the X chromosome and is subject to inactivation by DNA methylation. The encoded protein may be involved in regulation of organogenesis and myogenesis, and may play a role in premature ovarian failure. Multiple transcript variants encoding different isoforms have been found for this gene. |
