金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting

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      • POU5F1抗原(重组蛋白)

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        • 品牌 : 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物
        • 目录号 : TW17066
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      中文名称: POU5F1抗原(重组蛋白)

      英文名称: POU5F1 Antigen (Recombinant Protein)

      别      名: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

      储      存: 冷冻(-20℃)

      相关类别: 抗原

      概述

      Fusion protein corresponding to a region derived from 1-150 amino acids of human POU5F1

      技术规格

      Full name:

      POU class 5 homeobox 1

      Synonyms:

      OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

      Swissprot:

      Q01860

      Gene Accession:

      BC117435

      Purity:

      >85%, as determined by Coomassie blue stained SDS-PAGE

      Expression system:

      Escherichia coli

      Tags:

      His tag C-Terminus, GST tag N-Terminus

      Background:

      This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development, especially during early embryogenesis, and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene, t(6;22)(p21;q12), has been linked to tumor formation. Alternative splicing, as well as usage of alternative translation initiation codons, results in multiple isoforms, one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.

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