Full name: |
Retinoic acid receptor, alpha |
Synonyms: |
RAR; NR1B1 |
Swissprot: |
P10276 |
Gene Accession: |
BC008727 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus. |