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中文名称： FAIM2抗原（重组蛋白）
英文名称： FAIM2 Antigen (Recombinant Protein)
别 名： LFG; LFG2; NGP35; NMP35; TMBIM2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to N terminal 105 amino acids of human FAIM2 |
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Full name: |
Fas apoptotic inhibitory molecule 2 |
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Synonyms: |
LFG; LFG2; NGP35; NMP35; TMBIM2 |
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Swissprot: |
Q9BWQ8 |
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Gene Accession: |
BC000051 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
FAIM2 (Fas apoptotic inhibitory molecule 2), also known as LFG (Protein lifeguard), TMBIM2 (Transmembrane BAX inhibitor motif-containing protein 2) and NMP35 (neural membrane protein 35), is a 316 amino acid multipass membrane protein that uniquely protects cells from Fas-induced apoptosis. Though widely expressed, FAIM2 expression is highest in hippocampus. FAIM2 contains seven transmembrane domains and resembles Bax Inhibitor-1, another anti-apoptotic protein. Overexpression of FAIM2 results in decreased caspase activation and reduced incidence of programmed cell death. |
