金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting

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    • XRCC6抗原(重组蛋白)

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      • 品牌 : 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物
      • 目录号 : TW17336
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    中文名称: XRCC6抗原(重组蛋白)

    英文名称: XRCC6 Antigen (Recombinant Protein)

    别       名: ML8, KU70, TLAA, CTC75, CTCBF, G22P1

    储       存: 冷冻(-20℃)

    相关类别: 抗原

    概述

    Fusion protein corresponding to a C terminal 300 amino acids of human XRCC6

    技术规格

    Full name:

    X-ray repair complementing defective repair in Chinese hamster cells 6

    Synonyms:

    ML8, KU70, TLAA, CTC75, CTCBF, G22P1

    Swissprot:

    P12956

    Gene Accession:

    BC008343

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The p70/p80 autoantigen is a nuclear complex consisting of 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.


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