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中文名称： HSD17B2抗原（重组蛋白）
英文名称： HSD17B2 Antigen (Recombinant Protein)
别 名： HSD17; SDR9C2; EDH17B2
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 120-387 amino acids of human HSD17B2 |
|
Full name: |
hydroxysteroid (17-beta) dehydrogenase 2 |
|
Synonyms: |
HSD17; SDR9C2; EDH17B2 |
|
Swissprot: |
P37059 |
|
Gene Accession: |
BC009581 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
17β-HSD2 (17β hydroxysteroid dehydrogenase type 2) belongs to the 17β-HSD family of proteins that regulate the availability of steroids within a tissue. 17β-HSD2 converts active steroids to their inactive form through its oxidative activity. It is a key player in the inactivation of Estradiol and testosterone. Due to the affects that 17β-HSD2 has on the availability of estrogen, it has been extensively investigated for playing a possible role in breast tumor development, colon cancer development and the pathophysiology of endometriosis. |
