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中文名称： SUV39H1抗原（重组蛋白）
英文名称： SUV39H1 Antigen (Recombinant Protein)
别 名： MG44; KMT1A; SUV39H; H3-K9-HMTase 1
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 243-396 amino acids of human SUV39H1 |
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Full name: |
suppressor of variegation 3-9 homolog 1 |
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Synonyms: |
MG44; KMT1A; SUV39H; H3-K9-HMTase 1 |
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Swissprot: |
O43463 |
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Gene Accession: |
BC006238 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes an evolutionarily-conserved protein containing an N-terminal chromodomain and a C-terminal SET domain. The encoded protein is a histone methyltransferase that trimethylates lysine 9 of histone H3, which results in transcriptional gene silencing. Loss of function of this gene disrupts heterochromatin formation and may cause chromosome instability. Alternative splicing results in multiple transcript variants. |
