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中文名称： 兔抗MASP1多克隆抗体
英文名称： Anti-MASP1 rabbit polyclonal antibody
别 名： 3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1
抗 原： MASP1
储 存： 冷冻（-20℃）
宿 主： Rabbit
相关类别： 一抗
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes a serine protease that functions as a component of the lectin pathway of complement activation. The complement pathway plays an essential role in the innate and adaptive immune response. The encoded protein is synthesized as a zymogen and is activated when it complexes with the pathogen recognition molecules of lectin pathway, the mannose-binding lectin and the ficolins. This protein is not directly involved in complement activation but may play a role as an amplifier of complement activation by cleaving complement C2 or by activating another complement serine protease, MASP-2. The encoded protein is also able to cleave fibrinogen and factor XIII and may may be involved in coagulation. A splice variant of this gene which lacks the serine protease domain functions as an inhibitor of the complement pathway. Alternate splicing results in multiple transcript variants. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
MASP1 |
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Immunogen: |
Fusion protein of human MASP1 |
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Full name: |
mannan binding lectin serine peptidase 1 |
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Synonyms: |
3MC1; MAP1; MASP; RaRF; CRARF; MASP3; MAp44; PRSS5; CRARF1 |
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SwissProt: |
P48740 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human prostate cancer and Human breast cancer |
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IHC Recommend dilution: |
100-300 |
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WB Predicted band size: |
79 kDa |
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WB Positive control: |
Human heart tissue and Hela cell lysates |
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WB Recommended dilution: |
500-2000 |
