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中文名称：IRAK4抗原（重组蛋白）
英文名称： IRAK4 Antigen (Recombinant Protein)
别 名： IPD1; REN64; IRAK-4; NY-REN-64
储 存： 冷冻（-20℃）
相关类别： 抗原
概述
|
usion protein corresponding to a region derived from 186-454 amino acids of human IRAK4 |
|
Full name: |
interleukin-1 receptor-associated kinase 4 |
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Synonyms: |
IPD1; REN64; IRAK-4; NY-REN-64 |
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Swissprot: |
Q9NWZ3 |
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Gene Accession: |
BC013316 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. |
