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    • 兔抗MCM3多克隆抗体

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      价格:
      • 品牌 : 通蔚生物
      • 目录号 : TW18175
      • 应用 : 仅供科研使用
      • 货期 : 现货
      • 规格 :100ul/200ul/25ul
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    中文名称:   兔抗MCM3多克隆抗体


    英文名称:   Anti-MCM3 rabbit polyclonal antibody


    别      名:   HCC5, P1.h, RLFB, P1-MCM3


    抗     原:   MCM3


    储     存:   冷冻(-20℃)


    宿      主:   Rabbit


    相关类别:  一抗


    反应种属:  Human, Mouse


    标  记  物:  Unconjugate


    克隆类型:  rabbit polyclonal


    技术规格

    Background:

    The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

    Applications:

    ELISA, WB, IHC

    Name of antibody:

    MCM3

    Immunogen:

    Fusion protein of human MCM3

    Full name:

    minichromosome maintenance complex component 3

    Synonyms:

    HCC5, P1.h, RLFB, P1-MCM3

    SwissProt:

    P25205

    ELISA Recommended dilution:

    1000-5000

    IHC positive control:

    Human lung cancer

    IHC Recommend dilution:

    25-100

    WB Predicted band size:

    91 kDa

    WB Positive control:

    K562, Jurkat, hela and 293T cells

    WB Recommended dilution:

    500-2000







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