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中文名称： LBR 抗原（重组蛋白）
英文名称： LBR Antigen (Recombinant Protein)
别 名： lamin B receptor; PHA; LMN2R; TDRD18; DHCR14B
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述
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Fusion protein corresponding to N terminal 210 amino acids of human LBR |
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Full name: |
lamin B receptor |
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Synonyms: |
PHA; LMN2R; TDRD18; DHCR14B |
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Swissprot: |
Q14739 |
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Gene Accession: |
BC020079 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo transcript variants encoding the same protein have been identified. |
