Background: |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. |
Applications: |
ELISA, IHC |
Name of antibody: |
DKK3 |
Immunogen: |
Fusion protein of human DKK3 |
Full name: |
dickkopf WNT signaling pathway inhibitor 3 |
Synonyms: |
RIG; REIC |
SwissProt: |
Q9UBP4 |
ELISA Recommended dilution: |
1000-2000 |
IHC positive control: |
Human thyroid cancer and human gastric cancer |
IHC Recommend dilution: |
25-100 |