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Background: |
DnaJ homolog subfamily B member 1 is a protein that in humans is encoded by the DNAJB1 gene. Heat shock protein 40 (HSP 40) family proteins bind to HSP 70 through their J-domain and regulate the function of HSP 70 by stimulating HSP 70 ATPase activity. HSP 40, also known as DnaJ, functions together with DnaK (HSP 70) and GrpE as a molecular chaperone, involving them in assembly and disassembly of protein complexes, protein folding, renaturation of denatured proteins, prevention of protein aggregation and protein export. HSP 40 stimulates the association be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen HSC 70 and HIP and translocates rapidly from the cytoplasm to the nuclei, and especially to the nucleoli, upon heat shock. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
DNAJB1 |
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Immunogen: |
Fusion protein of human DNAJB1 |
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Full name: |
DnaJ (Hsp40) homolog, subfamily B, member 1 |
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Synonyms： |
Hdj1; Sis1; HSPF1; Hsp40; RSPH16B |
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SwissProt: |
P25685 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human lung cancer and human gastric cancer |
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IHC Recommend dilution: |
25-100 |
