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中文名称：GUSB抗原（重组蛋白）
英文名称： GUSB Antigen (Recombinant Protein)
别 名： BG; MPS7
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
|
Fusion protein corresponding to a region derived from 452-651 amino acids of human GUSB |
|
Full name: |
glucuronidase beta |
|
Synonyms: |
BG; MPS7 |
|
Swissprot: |
P08236 |
|
Gene Accession: |
BC014142 |
|
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
|
Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a hydrolase that degrades glycosaminoglycans, including heparan sulfate, dermatan sulfate, and chondroitin-4,6-sulfate. The enzyme forms a homotetramer that is localized to the lysosome. Mutations in this gene result in mucopolysaccharidosis type VII. Alternative splicing results in multiple transcript variants. There are many pseudogenes of this locus in the human genome. |
