Background: |
The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo transcript variants encoding distinct isoforms. |
Applications: |
ELISA, IHC |
Name of antibody: |
DSC1 |
Immunogen: |
Synthetic peptide of human DSC1 |
Full name: |
desmocollin 1 |
Synonyms: |
CDHF1; DG2/DG3 |
SwissProt: |
Q08554 |
IHC positive control: |
Human gastric cancer and human brain |
IHC Recommend dilution: |
50-200 |