Name: IDO2抗原（重组蛋白）
Brand: 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物

中文名称： IDO2抗原（重组蛋白）

英文名称： IDO2 Antigen (Recombinant Protein)

别名： INDOL1

储存： 冷冻（-20℃）

相关类别：抗原

概述

Full length fusion protein

技术规格

Full name:	indoleamine 2,3-dioxygenase 2
Synonyms:	INDOL1
Swissprot:	Q6ZQW0
Gene Accession:	BC113496
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	INDOL1 is also known as IDO2 (indoleamine 2,3-dioxygenase 2) and is a 407 amino acid protein that is expressed in various tissues, including liver, small intestine, spleen, placenta, thymus, lung, brain, kidney, colon and dendritic cells. INDOL1 is selectively inhibited by D-1MT (1-methyl-d-tryptophan), which also inhibits IDO (indoleamine 2,3-dioxygenase) and is significant because IDO expression causes suppression of T cell responses to tumors in dendritic cells. The inhibition of INDOL1 by D-1MT suggests a common function in immunomodulation. In the human INDOL1 gene, 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo single nucleotide polymorphisms have been detected which abolish the enzymatic function of INDOL1.

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金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting

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