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021-54845833/15800441009
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Background: |
This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. |
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Applications: |
WB |
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Name of antibody: |
ERBB4(Phospho-Tyr1284) |
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Immunogen: |
Peptide sequence around phosphorylation site of Tyrosine 1284 (P-E-Y(p)-L-S) derived from Human HER4 |
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Full name: |
v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 |
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Synonyms： |
HER4; ALS19; p180erbB4 |
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SwissProt: |
Q15303 |
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WB Predicted band size: |
147 kDa |
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WB Positive control: |
Huvec cells lysates treated with EGF |
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WB Recommended dilution: |
500-1000 |
