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概 述
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Full name: |
serine/threonine kinase receptor associated protein |
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Synonyms: |
MAWD; PT-WD; UNRIP |
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Swissprot: |
Q9Y3F4 |
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Gene Accession: |
BC000162 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAPgene. The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. |
