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中文名称： 兔抗PDGFB多克隆抗体
英文名称： Anti-PDGFB rabbit polyclonal antibody
别 名： SIS, SSV, PDGF2, c-sis
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： PDGFB
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations be金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingeen chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PDGFB |
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Immunogen: |
Synthetic peptide of human PDGFB |
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Full name: |
Platelet-derived growth factor beta polypeptide |
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Synonyms： |
SIS, SSV, PDGF2, c-sis |
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SwissProt: |
P01127 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human liver cancer and Human ovarian cancer |
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IHC Recommend dilution: |
50-200 |
