购物车
帮助
021-54845833/15800441009
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Background: |
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SMAD7 |
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Immunogen: |
Synthetic peptide of human SMAD7 |
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Full name: |
SMAD family member 7 |
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Synonyms： |
CRCS3, MADH7, MADH8 |
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SwissProt: |
O15105 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |
