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Background: |
Sperm-associated antigen 5 is a protein that in humans is encoded by the SPAG5 gene. This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles. Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SPAG5 |
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Immunogen: |
Fusion protein of human SPAG5 |
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Full name: |
sperm associated antigen 5 |
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Synonyms： |
MAP126; DEEPEST; hMAP126 |
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SwissProt: |
Q96R06 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
