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Background: |
This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SRGN |
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Immunogen: |
Fusion protein of human SRGN |
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Full name: |
serglycin |
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Synonyms： |
PPG; PRG; PRG1 |
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SwissProt: |
P10124 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
