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中文名称：兔抗ATP6V0D1多克隆抗体
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Background: |
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
ATP6V0D1 |
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Immunogen: |
Fusion protein of human ATP6V0D1 |
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Full name: |
ATPase H+ transporting V0 subunit d1 |
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Synonyms: |
P39; VATX; VMA6; ATP6D; ATP6DV; VPATPD |
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SwissProt: |
P61421 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer; |
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IHC Recommend dilution: |
25-100 |
