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中文名称：兔抗BAK1多克隆抗体
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Background: |
The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
BAK1 |
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Immunogen: |
Fusion protein of human BAK1 |
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Full name: |
BCL2-antagonist/killer 1 |
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Synonyms： |
BAK; CDN1; BCL2L7; BAK-LIKE |
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SwissProt: |
Q16611 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human esophagus cancer and human breast cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
23 kDa |
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WB Positive control: |
Hela, A431, 293T and Jurkat cells |
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WB Recommended dilution: |
1000-5000 |
