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中文名称：兔抗BRAF(Phospho-Thr599) 多克隆抗体
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Background: |
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. |
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Applications: |
IHC |
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Name of antibody: |
BRAF(Phospho-Thr599) |
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Immunogen: |
Peptide sequence around phosphorylation site of threonine 599 (L-A-T(p)-V-K) derived from Human B-RAF. |
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Full name: |
B-Raf proto-oncogene, serine/threonine kinase |
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Synonyms： |
NS7; BRAF1; RAFB1; B-RAF1 |
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SwissProt: |
P15056 |
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IHC positive control: |
Human breast carcinoma tissue |
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IHC Recommend dilution: |
50-100 |
