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中文名称： CD247抗原（重组蛋白）
英文名称： CD247 Antigen (Recombinant Protein)
别 名： CD247 molecule; T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA
储 存： 冷冻（-20℃）
相关类别：抗原
技术规格
|
Full name: |
CD247 molecule |
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Synonyms: |
T3Z; CD3H; CD3Q; CD3Z; TCRZ; IMD25; CD3-ZETA |
|
Swissprot: |
P20963 |
|
Gene Accession: |
BC025703 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
