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    • 品牌 : 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物
    • 目录号 : TW4308
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中文名称:兔抗CASP10多克隆抗体

英文名称:
Anti-CASP10 rabbit polyclonal antibody

别      名: caspase 10 MCH4; ALPS2; FLICE2

相关类别: 一抗

储      存: 冷冻(-20℃)

宿      主:
Rabbit

抗      原: CASP10

反应种属: Human

标 记 物:
Unconjugate

克隆类型: rabbit polyclonal

技术规格

Background:

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Applications:

ELISA, IHC

Name of antibody:

CASP10

Immunogen:

Synthetic peptide of human CASP10

Full name:

caspase 10

Synonyms:

MCH4; ALPS2; FLICE2

SwissProt:

Q92851

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human esophagus cancer; Human ovarian cancer

IHC Recommend dilution:

20-100





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