中文名称:兔抗CASP10多克隆抗体
英文名称: Anti-CASP10 rabbit polyclonal antibody
别 名: caspase 10 MCH4; ALPS2; FLICE2
相关类别: 一抗
储 存: 冷冻(-20℃)
宿 主: Rabbit
抗 原: CASP10
反应种属: Human
标 记 物: Unconjugate
克隆类型: rabbit polyclonal
技术规格
Background: |
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Applications: |
ELISA, IHC |
Name of antibody: |
CASP10 |
Immunogen: |
Synthetic peptide of human CASP10 |
Full name: |
caspase 10 |
Synonyms: |
MCH4; ALPS2; FLICE2 |
SwissProt: |
Q92851 |
ELISA Recommended dilution: |
5000-10000 |
IHC positive control: |
Human esophagus cancer; Human ovarian cancer |
IHC Recommend dilution: |
20-100 |