金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting

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      • 品牌 : 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meeting生物
      • 目录号 : TW4857
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    中文名称:兔抗CCR1多克隆抗体

    英文名称:
    Anti-CCR1 rabbit polyclonal antibody

    别      名: C-C motif chemokine receptor 1; CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1

    相关类别: 一抗

    储      存: 冷冻(-20℃)

    宿      主: Rabbit

    抗      原: CCR1

    反应种属: Human, Mouse

    标 记 物: Unconjugate

    克隆类型: rabbit polyclonal

    技术规格

    Background:

    This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p.

    Applications:

    ELISA, WB

    Name of antibody:

    CCR1

    Immunogen:

    Synthetic peptide of human CCR1

    Full name:

    C-C motif chemokine receptor 1

    Synonyms:

    CKR1; CD191; CKR-1; HM145; CMKBR1; MIP1aR; SCYAR1

    SwissProt:

    P32246

    ELISA Recommended dilution:

    5000-10000

    WB Predicted band size:

    41 kDa

    WB Positive control:

    Mouse heart tissue and Mouse brain tissue lysates

    WB Recommended dilution:

    200-1000




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