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中文名称：TCAP 抗原（重组蛋白）
英文名称：TCAP Antigen (Recombinant Protein)
别 名： titin-cap; TELE; CMD1N; CMH25; T-cap; LGMD2G; LGMDR7; telethonin
储 存： 冷冻（-20℃）
相关类别：抗原
概 述
技术规格
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Full name: |
titin-cap |
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Synonyms: |
TELE; CMD1N; CMH25; T-cap; LGMD2G; LGMDR7; telethonin |
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Swissprot: |
O15273 |
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Gene Accession: |
BC013330 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Sarcomere assembly is regulated by the muscle protein titin. Titin is a giant elastic protein with kinase activity that extends half the length of a sarcomere. It serves as a scaffold to which myofibrils and other muscle related proteins are attached. This gene encodes a protein found in striated and cardiac muscle that binds to the titin Z1-Z2 domains and is a substrate of titin kinase, interactions thought to be critical to sarcomere assembly. Mutations in this gene are associated with limb-girdle muscular dystrophy type 2G. |
