Name: UACA 抗原（重组蛋白）
Brand: 通蔚生物

中文名称： UACA 抗原（重组蛋白）

英文名称： UACA Antigen (Recombinant Protein)

别名： uveal autoantigen with coiled-coil domains and ankyrin repeats; NUCLING

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to C terminal 200 amino acids of human UACA

技术规格

Full name:	uveal autoantigen with coiled-coil domains and ankyrin repeats
Synonyms:	NUCLING
Swissprot:	Q9BZF9
Gene Accession:	BC113407
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	Regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. Promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. Regulates the redistribution of APAF1 into the nucleus after proapoptotic stress. Down-regulates the expression of LGALS3 by inhibiting NFKB1 (By similarity).

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