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中文名称：小鼠抗AMACR(C-term)单克隆抗体
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Background: |
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. |
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Applications: |
WB, IF |
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Name of antibody: |
AMACR(C-term) |
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Immunogen: |
Fusion protein of human AMACR |
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Full name: |
alpha-methylacyl-CoA racemase |
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Synonyms: |
RM; RACE; CBAS4; P504S; AMACRD |
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SwissProt: |
Q9UHK6 |
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WB Predicted band size: |
42 kDa |
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WB Positive control: |
Rat Liver tissue lysate |
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WB Recommended dilution: |
1000-5000 |
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IF positive control: |
Jurkat cells |
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IF Recommend dilution: |
50-100 |
