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021-54888888/15800441009
中文名称：小鼠抗ARRB1单克隆抗体
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Background: |
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. |
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Applications: |
WB |
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Name of antibody: |
ARRB1 |
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Immunogen: |
Fusion protein of human ARRB1 |
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Full name: |
arrestin beta 1 |
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Synonyms: |
ARB1; ARR1 |
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SwissProt: |
P49407 |
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WB Predicted band size: |
47 kDa |
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WB Positive control: |
K562 and Hela cell lysates |
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WB Recommended dilution: |
500-2000 |
