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021-54888888/15800441009
中文名称： ZUP1 抗原（重组蛋白）
英文名称： ZUP1 Antigen (Recombinant Protein)
别 名： zinc finger containing ubiquitin peptidase 1; DUB; ZUFSP; C6orf113
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
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Full name: |
zinc finger containing ubiquitin peptidase 1 |
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Synonyms: |
DUB; ZUFSP; C6orf113 |
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Swissprot: |
Q96AP4 |
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Gene Accession: |
BC016879 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a protein containing zinc finger motifs and a cysteine peptidase domain. The encoded protein functions as a K63-specific de-ubiquitinating enzyme that specifically cleaves long K63-linked polyubiquitin chains in the middle of a chain (i.e. "endo cleavage) rather than by removing the terminal ubiquitin from a chain. This enzyme is thought to be involved in the regulation of DNA repair by cleaving K63-linked ubiquitin chains at repair foci. This protein is related to proteases for the ubiquitin-like modifiers Ufm1 (ubiquitin fold modifier 1) and Atg8/Gabarapl2, but does not have any activity on these modifiers. [provided by RefSeq, Mar 2018] |
