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021-54845833/15800441009
中文名称 : 小鼠抗METAP2单克隆抗体
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Background: |
This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]. |
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Applications: |
WB, IHC, IF, FC |
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Name of antibody: |
METAP2 |
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Immunogen: |
Fusion protein of human METAP2 |
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Full name: |
methionyl aminopeptidase 2 (METAP2) |
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Synonyms: |
MAP2; MNPEP; p67; p67eIF2 |
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SwissProt: |
P50579 |
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IHC positive control: |
human pancreas tissue and carcinoma of human thyroid tissue; carcinoma of human prostate tissue and human breast tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
53 kDa |
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WB Positive control: |
HepG2, Hela, A549, COS7, Jurkat, PC-12 cell lysates |
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WB Recommended dilution: |
500-2000 |
