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中文名称：ALDOA抗原（重组蛋白）
英文名称：ALDOA Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
Fusion protein corresponding to C terminal 200 amino acids of human ALDOA
技术规格
Full name:
Aldolase A, fructose-bisphosphate
Synonyms:
ALDA; GSD12
Swissprot:
P04075
Gene Accession:
BC004333
Purity:
>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:
Escherichia coli
Tags:
His tag C-Terminus, GST tag N-Terminus
Background:
The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10.
