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    • APLP1抗原(重组蛋白)

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    中文名称:APLP1抗原(重组蛋白)

    英文名称:
    APLP1 Antigen (Recombinant Protein)

    储      存:
    冷冻(-20℃)

    相关类别:抗原

    概述

    Fusion protein corresponding to a region derived from 56-342 of human APLP1


    技术规格

    Full name:

    Amyloid beta (A4) precursor-like protein 1

    Synonyms:

    APLP

    Swissprot:

    P51693

    Gene Accession:

    BC012889

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the highly conserved amyloid precursor protein gene family. The encoded protein is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage. This cleavage liberates an intracellular cytoplasmic fragment that may act as a transcriptional activator. The encoded protein may also play a role in synaptic maturation during cortical development. Alternatively spliced transcript variants encoding different isoforms have been described.


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