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中文名称：BACE1抗原（重组蛋白）
英文名称：BACE1 Antigen (Recombinant Protein)
储 存：冷冻（-20℃）
相关类别：抗原
概述
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Fusion protein corresponding to C terminal 300 amino acids of human BACE1 |
技术规格
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Full name: |
beta-site APP-cleaving enzyme 1 |
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Synonyms: |
ASP2; BACE; HSPC104 |
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Swissprot: |
P56817 |
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Gene Accession: |
BC065492 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. |
