中文名称:CCL21抗原(重组蛋白)
英文名称:CCL21 Antigen (Recombinant Protein)
储 存:冷冻(-20℃)
相关类别:抗原
概述
Fusion protein corresponding to a region derived from 24-134 amino acids of human CCL21 |
技术规格
Full name: |
chemokine (C-C motif) ligand 21 |
Synonyms: |
ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21 |
Swissprot: |
O00585 |
Gene Accession: |
BC027918 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by 金年会·(jinnianhui)金字招牌诚信至上-Gold Annual Meetingo adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). |